The authors also reviewed hormonal changes, but did not discuss the issue of fertility. However, when comparing different treatment groups, identical trends were found regardless of method. We apologize for the inconvenience, but your browser is currently not supported by this website. Although the results presented here are valuable, this review has limitations that should be considered. Semen analysis reports consisted primarily of sperm count, motility, and morphology Fig. Differences in nuclear DNA fragmentation and mitochondrial integrity of semen and prepared human spermatozoa.
In conclusion, irradiation induced an increase in the number of sperms with DNA damage, lasting for at least 1—2 years post-therapy, whereas more than two cycles of chemotherapy reduced the proportion of sperms with impaired DNA integrity.
Testicular Cancer & Male Infertility
The testicles are where sperm are made. The small number of studies available on this topic that were observational studies limits our findings, but at the same time highlights that this issue requires further investigation. Sperm concentration is negatively affected by cancer treatment, the extent depending on both type of therapy and dosage Eberhard et al. Find articles by Krystal Hays. Author Disclosure Statement No competing financial interests exist.